Ancient and modern genome-wide studies converge on a broad result: many Jewish populations and Palestinian/other Levantine Arabic-speaking populations preserve substantial ancestry related to ancient inhabitants of the Levant. The 2020 Southern Levant ancient-DNA study modeled most sampled Jewish groups and Levantine Arabic-speaking groups with large contributions from ancient Middle Eastern sources related to Bronze Age Southern Levantines and neighboring populations. That is evidence for deep regional continuity, not a claim of descent from the exact ancient individuals sampled.
Direct comparisons also recover shared ancestry between Jews and Palestinians. A high-resolution Y-chromosome study of Israeli and Palestinian Arabs found substantial overlap with Jewish paternal haplotypes and inferred a shared ancestral pool for a large portion of the sampled Y chromosomes, while also detecting divergence and later admixture.
The later history matters just as much. Genome-wide work on the Levant shows that Arabization and Islamization were cultural-demographic processes accompanied by gene flow, not wholesale replacement of the pre-existing Levantine population. Modern Levantines remain genetically distinguishable from populations of the Arabian Peninsula, even though Muslim Levantine groups received additional Arabian and African-related ancestry during the last two millennia.
Most defensible summaryPalestinians are best described genetically as a modern Levantine population shaped by long local continuity, Arabization, Islamization and later admixture. Many Jewish populations preserve ancestry from the same ancient Levantine population substrate, followed by diaspora-specific admixture, bottlenecks and endogamy.
Why “Palestinians are Arabized Jews” goes too farSome Palestinian ancestors were almost certainly Jews, Samaritans, Christians and members of other long-resident Levantine communities, but current genetics cannot isolate what percentage came specifically from ancient Jews. Iron Age Israelites/Judeans themselves shared much of the wider southern-Levantine genetic substrate, and representative genome-wide DNA from Iron Age Israel and Judah remains sparse.